Does Taking CBD Oil with Other Medication Cause Drug Interactions?

CBD is a trending supplement in the wellness industry. Many people are buying CBD oil to take advantage of its therapeutic benefits. But what would happen if you took CBD along with prescription drugs? Would it cause problems?

CBD, short for cannabidiol, is a non-psychotropic cannabis compound. Humans have been taking it since the dawn of time but have only been legalized in Europe and America in recent times.

Most people take CBD for its potential to enhance their well-being. As long as you get the dosage right, you’re unlikely to experience any side effects.

If you ingest CBD while you’re on other medication, the results are typically uncertain. In some cases, there might not be any side effects, but in other cases, there may be issues.

The chemical compounds in CBD can potentially react against the chemical compounds of your prescription drugs in a process known as drug interaction [1].

What Medical Issues Can CBD Help Manage?

Even though CBD is legal at the state and federal levels, certain legal provisions govern its extraction and sale.

For instance, CBD merchants may not market CBD products as having any medical benefits. They are instead supposed to be marketed as health supplements. But there’s an exception.

Epidiolex is the only CBD-based product that the FDA has approved to be marketed as a medical product. Epidiolex helps with managing epileptic seizures [2].

One of the reasons why CBD has not been approved for medical use by the FDA is down to limited scientific research on hemp-derived CBD.

But then anecdotal evidence suggests that CBD does have numerous therapeutic advantages. There are tons of people who have ditched OTC drugs in favor of CBD for managing certain health issues.

But what are some of these health problems that can be managed through consuming CBD regularly?

Pain: many people experience pain through injuries and autoimmune diseases. But pain typically denies you comfort. CBD has been suggested to help with eliminating pain.

Cancer: cancer has ballooned into a worldwide health crisis. Research performed on CBD suggests that it can help with inducing the death of cancer cells as well as inhibiting the migration of cancer cells [3].

Diabetes: diabetes is a chronic illness characterized by low insulin production or absorption. Research shows that CBD may help with minimizing the incidence of diabetes [4].

Is It Okay to Take CBD Along with Other Medications?

If you have a medical condition, you typically go to a health professional to get a diagnosis and treatment, which includes prescription drugs. But other issues may necessitate the consumption of CBD.

Some people take prescription drugs along with CBD products and don’t see any negative effects, but some people take prescription drugs along with CBD products and experience various negative effects.

However, to be on the safe side, if you’re planning to take CBD products, and are already on prescription drugs or planning to start taking them, it’s critical to visit a health professional who may help you navigate that.

And so, there’s nothing wrong with taking CBD if you’re sick.

How Can a Drug Interaction Affect You?

Supposing you ingest some CBD resources, and the cannabis molecules react against the chemical components of your prescription drugs, it can lead to various outcomes.

For one, a drug interaction can minimize the effectiveness of a drug. A drug interaction may lead to the degradation of prescription drugs and thus make them less useful.

A CBD drug interaction can potentially lead to side effects like stomach aches and drowsiness, thus causing you to feel uncomfortable.

In worst-case scenarios, a CBD drug interaction can lead to toxicity issues, especially if the prescription drug contains a few unstable or harmful compounds.

Is CBD Safe for Everyone?

The distinguishing trait of CBD is that it has no psychotropic effects, and so, one may not experience a mental high after consuming it.

People from all demographics typically enjoy CBD resources without getting intoxicated. But there are certain groups of people that are advised against taking CBD:

Pregnant and breastfeeding women: fetuses and infants are most vulnerable. But some CBD products can potentially contain chemical components that are harmful to fetuses and infants.

Doctor’s recommendation: as human beings, different factors determine our health status. And sometimes, you may not be in the proper health condition to ingest CBD. If your doctor advises you against taking CBD, you should heed their advice.

Common Drugs that Interact with CBD

The following are some of the drugs that commonly trigger drug interactions. If you’re taking them, or are planning to take them, you may want to avoid taking CBD.

Brivaracetam: this prescription drug is designed for managing seizures. Following an interaction, the ability of the body to break down and absorb the drug is typically lowered.

Caffeine: this is not necessarily a drug, but it’s consumed in diverse forms, and it can induce mild psychoactive effects. CBD interacts with caffeine and inadvertently raises caffeine levels.

Carbamazepine: this drug is usually prescribed for managing seizures, relieving pain, and managing bipolar disorder. It has been noted to have drug interaction potential that leads to diverse side effects.

Citalopram: this drug is usually prescribed for managing depression and eliminating panic attacks. It has been found to have drug interaction potential.

Everolimus: this drug is prescribed for its immunosuppressant properties as well as managing certain cancers. CBD doesn’t get along with this medication.

How to Buy High-Quality and Safe CBD

Unless you consume quality and safe CBD products, you might end up not receiving the positive effects of CBD. The following are some of the things to consider when buying CBD:

CBD source: quality CBD is typically derived from organically-farmed industrial hemp with the best farming practices observed. The CBD is also processed with high standards in a GMP-certified facility.

Brand reputation: before purchasing a product, check to see what people are saying about the product and brand. It gives you a peek into the experience you’re going to have.

Lab reports: check to see that the product has lab reports. This is an indication that the CBD product has undergone independent lab testing. Independent lab tests help with verifying that the product doesn’t have any harmful agents like pesticides.

The Takeaway: CBD and Drug Interaction

Many people are turning to CBD products to experience their amazing therapeutic effects. But if you take CBD along with certain medication, it can lead to a drug interaction. If you have a pre-existing health issue or are on medication, always make a point of talking with your doctor before you start taking CBD. Their advice may help you evade drug interactions.


  • Brown, J. D., & Winterstein, A. G. (2019). Potential adverse drug events and drug-drug interactions with medical and consumer cannabidiol (CBD) use. Journal of clinical medicine8(7), 989.
  • Abu-Sawwa, R., & Stehling, C. (2020). Epidiolex (cannabidiol) primer: frequently asked questions for patients and caregivers. The Journal of Pediatric Pharmacology and Therapeutics25(1), 75-77.
  • Seltzer, E. S., Watters, A. K., MacKenzie, D., Granat, L. M., & Zhang, D. (2020). Cannabidiol (CBD) as a promising anti-cancer drug. Cancers12(11), 3203.
  • Lehmann, C., Fisher, N. B., Tugwell, B., Szczesniak, A., Kelly, M., & Zhou, J. (2016). Experimental cannabidiol treatment reduces early pancreatic inflammation in type 1 diabetes. Clinical hemorheology and microcirculation64(4), 655-662.

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